April is dedicated to Rosacea Awareness month. It was established to educate the public about the impact of this chronic and widespread facial condition that is estimated to affect more than 415 million people worldwide. In honor of Rosacea Awareness Month, we want to share knowledge about this skin condition and how azelaic acid can contribute to its treatment.
Background information on this skin condition:
Rosacea is a recurring skin disease that mostly affects the face, but it can also affect the ears, back, and stomach. Acne-like bumps or pustules may also appear in certain patients.
Rosacea can be caused by a variety of factors. Although no cause has been identified, experts believe that one or more of the following causes could be to blame:
- Since rosacea continues to run in families, genetics plays a role.
- A response of the immune system to the bacterium Bacillus oleronius.
- Cathelicidin levels that are higher than average can cause inflammation, resulting in redness and bumps.
- Demodex, a mite that resides on everyone’s skin, may also be to blame. Researchers discovered that people with rosacea have more of these mites than others, but people without rosacea still have significant populations of demodex mites, indicating that more research is required.
The symptoms of rosacea include facial redness, tiny red pimples and fine red lines (telangiectasia [spider veins]) on the facial skin. Spider veins are small, dilated blood vessels near the surface of the skin. These spider veins may also show up on other parts of the body such as the lower & upper extremities. There are not too many medications for rosacea, and except for azelaic acid and particular flavonoids, all of these are pharmaceutical by nature.
In the three tables below, the different drugs used to treat rosacea are discussed on the basis of: Applicability, Functionality and Adverse Effects.
How can azelaic acid help with rosacea?
Azelaic acid has been demonstrated to be effective for the treatment of rosacea. It reduces inflammatory lesions and erythema in rosacea patients and also inhibits neutrophilic ROS (Reactive Oxygen Species). In the neutrophil system azelaic acid inhibits the ROS formation in a dose-dependent manner, markedly decreasing the number of free radicals. The major advantage of azelaic acid is that it lacks the side effects of the pharmaceutical ingredients.
Azelaic acid is increasingly used in products to combat rosacea. And this is an important advance in order to be able to treat the skin condition ever better. Would you like to receive more information about azelaic acid? Please feel free to contact us.